Sinus Endoscopy with Biopsy

This is an examination of the nasal cavity and sinuses using a thin, lighted tube. A small piece of abnormal tissue is taken for biopsy.

This is an examination of the nasal cavity and sinuses using a thin, lighted tube. A small piece of abnormal tissue is taken for biopsy.

Nasal endoscopy is an examination of the inside of the nose and sinuses by placing a lighted tube into the nose. When a biopsy is done, a piece of abnormal tissue or polyp is removed and sent to the lab for further testing. Your healthcare provider may suggest this procedure if you have symptoms that involve your nasal cavity and sinuses. This commonly includes obstructed nasal breathing that has not responded to conservative treatments. These treatments may include antihistamines and steroid nasal sprays.

  • The sinuses are air-filled spaces located behind the forehead, nasal bones, cheeks and eyes.
  • Normally, mucus drains from the sinuses so air can flow freely.
  • Occasionally, swelling or growths, such as polyps, can block the nasal passages. This stops the mucus from draining, which can lead to infection and symptoms of pain and pressure.

Nasal endoscopy with biopsy can be done in an office, hospital or ambulatory surgery center (ASC). During the procedure, you will most likely be awake. However, your nose will be numbed and you may receive medication to keep you relaxed.

  • When tissue is being removed, you may feel some discomfort, such as a pulling sensation or pressure in your nose.
  • The area where the tissue was removed may be sore and bleed for a few days. Do not blow your nose during this time. If there is any bleeding, apply pressure by gently squeezing your nose.
  • Make plans to have someone drive you home after the procedure.

Prior to the procedure, tell your healthcare provider about any medications you are taking (including over-the-counter medications and supplements). Ask about specific instructions you should follow before and after the surgery. These may include:

  • Medications you should not take before the procedure, such as blood thinners or aspirin
  • Regular medications you should continue to take on the day of your procedure
  • How many hours you should stop eating and drinking before the procedure

What should I ask my healthcare provider before having nasal endoscopy with biopsy?

  • What is my diagnosis and reason for the procedure?
  • What are the possible complications for this procedure?
  • Are there any alternatives to this procedure? What are the benefits and risks of each?
  • Is there any special preparation for the procedure? (If so, get clear instructions on what you need to do.)
  • Will I have any type of sedation? What are the possible side effects?
  • How will I feel after the procedure and will I have to modify my activity?

After your nasal endoscopy, your healthcare provider should provide a description of any problems found during the procedure, how they were handled and what symptoms you should report. You should also understand all home care instructions, including:

  • Medications and side effects
  • Follow-up plans
  • How and when you will be notified of any biopsy results


Also known as:

Sinus Endoscopy with Biopsy
Sinus Endoscopy
Sinus Debridement
Polyp Removal
Nasal Endoscopy
Nasal Debridement
Nasal Biopsy
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